ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. V. CHEMICAL COMPOSITION OF ENZYMATICALLY SYNTHESIZED DEOXYRIBONUCLEIC ACID

Enzymatic Synthesis of Deoxyribonucleic Acid. v. Chemical Composition of Enzymatically Synthesized Deoxyribonucleic Acid.

* This work has been supported in part by a research grant from the Nutrition Foundation. t Fellow of the Netherlands Organization for Pure Research (Z.W.O.). 1 T. Baranowski, B. Illingworth, D. H. Brown, and C. F. Cori, Biochim. et Biophys. Acta, 25, 16, 1957. 2 C. F. Cori and B. Illingworth, these PROCEEDINGS, 43, 547, 1957. 3 M. Cohn and G. T. Cori, J. Biol. Chem., 175, 89, 1948. 4The follow...

Enzymatic Synthesis of Deoxyribonucleic Acid. Deoxyribonucleic Acid By

MISSOURI The enzymatic synthesis of DNA1 in sufficient excess over the DNA used to prime the reaction21 a has enabled us to examine the chemical composition of the synthetic product. As has already been demonstrated, this DNA consists of deoxy-nucleotides Linked by typical 3'-5' phosphodiester bonds, and all four of the deoxy

Enzymatic synthesis of deoxyribonucleic acid.

Determination of deoxyribonucleotide sequence in a deoxyribonucleic acid molecule is important from both the chemical and genetic points of view. It is also essential for answering the question of whether DNA synthesized in vitro by polymerase (1, 2) is a faithful copy of the nucleotidel sequence of the primer DNA. Although enzymatically synthesized DNA has the same over-all nucleotide composit...

Enzymatic Synthesis of Deoxyribonucleic Acid. Iii. the Incorporation of Pyrimidine and Purine Analogues into Deoxyribonucleic Acid.

Enzymatic synthesis of deoxyribonucleic acid. VIII. Frequencies of nearest neighbor base sequences in deoxyribonucleic acid.

Determination of deoxyribonucleotide sequence in a deoxyribonucleic acid molecule is important from both the chemical and genetic points of view. It is also essential for answering the question of whether DNA synthesized in vitro by polymerase (1, 2) is a faithful copy of the nucleotidel sequence of the primer DNA. Although enzymatically synthesized DNA has the same over-all nucleotide composit...